:root{
  --ink:#111827; --muted:#475467; --line:#d0d5dd; --bg:#ffffff; --panel:#f8fafc;
  --teal:#075f78; --teal-dark:#03485d; --blue:#0b72e7; --soft:#eef7fb;
}
*{box-sizing:border-box} body{margin:0;background:var(--bg);color:var(--ink);font-family:Inter,ui-sans-serif,system-ui,-apple-system,BlinkMacSystemFont,"Segoe UI",sans-serif;line-height:1.58} a{color:#075f78}.site-nav{background:var(--teal);color:#fff}.nav-inner{max-width:1080px;margin:0 auto;padding:14px 22px;display:flex;align-items:center;justify-content:space-between;gap:20px}.brand{font-weight:850;color:#fff;text-decoration:none;letter-spacing:-.02em}.nav-links{display:flex;gap:18px;align-items:center;flex-wrap:wrap}.nav-links a{color:#eaf8fc;text-decoration:none;font-weight:750;font-size:13px}.nav-links a:hover,.nav-links a.active{color:#fff;text-decoration:underline;text-underline-offset:4px}.hero{background:linear-gradient(135deg,#075f78,#08799a);color:#fff}.hero-inner{max-width:1080px;margin:0 auto;padding:72px 22px 76px;display:grid;grid-template-columns:1.3fr .7fr;gap:44px;align-items:center}.hero h1{font-size:clamp(34px,4vw,54px);line-height:1.05;margin:0 0 18px;letter-spacing:-.045em}.hero p{font-size:18px;max-width:720px;margin:0;color:#edfaff}.hero-actions{display:flex;gap:12px;margin-top:30px;flex-wrap:wrap}.btn{display:inline-flex;align-items:center;justify-content:center;border-radius:3px;padding:13px 18px;text-decoration:none;font-weight:800;border:1px solid currentColor}.btn.primary{background:#fff;color:var(--teal);border-color:#fff}.btn.secondary{background:transparent;color:#fff;border-color:rgba(255,255,255,.7)}.hero-card{background:rgba(255,255,255,.12);border:1px solid rgba(255,255,255,.22);padding:26px;border-radius:6px}.hero-card div{font-weight:850;font-size:14px;text-transform:uppercase;letter-spacing:.06em;color:#dff8ff}.hero-card ul{margin:12px 0 0;padding-left:18px;color:#fff}.container{max-width:1080px;margin:0 auto;padding:48px 22px}.narrow{max-width:760px}.section-title{text-align:center;font-size:28px;letter-spacing:-.025em;margin:0 0 24px}.subhead{color:var(--muted);font-size:16px;margin-top:-8px;text-align:center}.two-col{display:grid;grid-template-columns:1fr 1fr;gap:28px}.cards{display:grid;grid-template-columns:repeat(3,1fr);gap:18px}.card{border:1px solid var(--line);background:#fff;border-radius:6px;padding:22px}.card h3{margin:0 0 8px;font-size:18px}.card p{margin:0;color:var(--muted);font-size:14px}.plain-section{border-top:1px solid var(--line)}.methods-layout{max-width:860px;margin:0 auto}.methods-section{border-top:1px solid var(--line);padding:30px 0}.methods-section:first-child{border-top:0;padding-top:0}.methods-section h2{font-size:24px;margin:0 0 14px;letter-spacing:-.02em}.methods-section p{color:#1f2937;margin:0 0 12px}.methods-section ul{margin:8px 0 0;padding-left:22px;color:#1f2937}.compact-list li{margin:6px 0}.team-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:16px}.team-card{border:1px solid var(--line);background:#fff;border-radius:6px;padding:18px}.team-card h3{margin:0 0 6px;font-size:18px}.team-card p{margin:0;color:var(--muted);font-size:14px}.team-note{margin-top:8px;color:#344054!important}.footer{background:#075f78;color:#e9f8fc;margin-top:40px}.footer-inner{max-width:1080px;margin:0 auto;padding:34px 22px;display:grid;grid-template-columns:1fr 1fr;gap:24px;font-size:13px}.footer strong{color:#fff}.footer a{color:#fff}.disclaimer{font-size:12px;color:#d4edf5;border-top:1px solid rgba(255,255,255,.18);padding-top:16px;margin-top:16px}.callout{background:var(--soft);border:1px solid #c8e7f1;border-radius:6px;padding:18px;color:#1f2937}.method-card-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:16px}.kicker{font-size:12px;text-transform:uppercase;letter-spacing:.08em;font-weight:850;color:#0b7285;margin-bottom:8px}.center{text-align:center}@media(max-width:800px){.hero-inner,.two-col,.cards,.team-grid,.method-card-grid,.footer-inner{grid-template-columns:1fr}.nav-inner{align-items:flex-start;flex-direction:column}.container{padding:36px 18px}.hero-inner{padding:54px 18px}.nav-inner{padding:14px 18px}}


/* Expanded clinician-facing methods page */
.methods-layout{max-width:900px}.methods-lead{font-size:17px;color:#1f2937;line-height:1.7;margin:0 auto 28px;max-width:820px}.method-subsection{margin:18px 0 0}.method-subsection h3{font-size:18px;margin:22px 0 8px;letter-spacing:-.01em}.figure-block{margin:26px 0 22px;border:1px solid var(--line);background:#fff;border-radius:8px;padding:18px}.figure-block img{width:100%;display:block;height:auto}.figure-caption{font-size:13px;color:#344054;margin-top:12px;line-height:1.55}.methods-table-wrap{overflow-x:auto;border:1px solid var(--line);border-radius:8px;background:#fff;margin-top:14px}.methods-table{width:100%;border-collapse:collapse;font-size:13px;min-width:720px}.methods-table th,.methods-table td{border-bottom:1px solid var(--line);padding:10px 12px;vertical-align:top;text-align:left}.methods-table th{background:#f8fafc;color:#344054;font-size:12px;text-transform:uppercase;letter-spacing:.05em}.methods-table tr:last-child td{border-bottom:0}.methods-table .group-row td{background:#eef7fb;color:#03485d;font-weight:850;border-top:1px solid #c8e7f1}.methods-table td:nth-child(2){white-space:nowrap}.term-list{display:grid;grid-template-columns:1fr 2fr;gap:0;border:1px solid var(--line);border-radius:8px;overflow:hidden;margin-top:14px}.term-list div{padding:10px 12px;border-bottom:1px solid var(--line)}.term-list div:nth-child(odd){font-weight:800;background:#f8fafc;color:#344054;border-right:1px solid var(--line)}.term-list div:nth-last-child(-n+2){border-bottom:0}.methods-note{font-size:13px;color:#475467;background:#f8fafc;border-left:4px solid var(--teal);padding:12px 14px;margin-top:14px}.section-anchor{scroll-margin-top:80px}
@media(max-width:800px){.term-list{grid-template-columns:1fr}.term-list div:nth-child(odd){border-right:0}.term-list div:nth-last-child(2){border-bottom:1px solid var(--line)}}

/* Homepage refinements */
.btn.wide{min-width:260px;padding-left:34px;padding-right:34px}
.output-list{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:12px;text-align:left;list-style:none;padding:0;margin:24px auto 0;max-width:720px}
.output-list li{border:1px solid var(--line);border-radius:6px;background:#fff;padding:14px 16px;color:#1f2937;font-weight:700}
@media(max-width:800px){.output-list{grid-template-columns:1fr}.btn.wide{width:100%;min-width:0}}


/* Homepage content and footer updates */
.home-hero{grid-template-columns:1fr;max-width:980px;text-align:center;padding-top:76px;padding-bottom:82px}
.home-hero-copy{max-width:860px;margin:0 auto}
.home-hero h1{margin-bottom:14px}
.home-hero p{margin:0 auto;color:#edfaff;font-size:20px;line-height:1.5;max-width:790px}
.home-actions{justify-content:center}
.home-section{padding-top:54px;padding-bottom:54px}
.home-text-block{max-width:890px;margin:0 auto;color:#1f2937;font-size:16px;line-height:1.75}
.home-text-block p{margin:0 0 18px}
.home-affiliation{text-align:center;font-weight:850;color:#03485d;margin:28px auto 0;font-size:15px;letter-spacing:.02em}
.research-section{background:#fff}
.research-application-list{display:grid;gap:14px;margin-top:30px}
.research-item{border:1px solid var(--line);background:#fff;border-radius:6px;overflow:hidden}
.research-heading{display:flex;align-items:center;gap:14px;padding:16px 22px;background:#f8fafc;border-bottom:1px solid var(--line)}
.research-number{font-weight:850;color:#1f2937;min-width:28px;text-align:right}
.research-heading h3{font-size:18px;margin:0;letter-spacing:-.01em}
.research-item p{margin:0;padding:20px 28px 22px 64px;color:var(--muted);font-size:15px;line-height:1.62}
.home-io-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:18px;margin-top:26px}
.io-card{border:1px solid var(--line);border-radius:6px;background:#fff;padding:22px}
.io-card h3{margin:0 0 10px;font-size:18px;letter-spacing:-.01em}
.io-card ul{margin:0;padding-left:20px;color:var(--muted);font-size:14px;line-height:1.7}
.scope-text{color:#1f2937;font-size:16px;line-height:1.75;margin:0;text-align:left}
.home-footer{margin-top:0;background:#075f78;color:#e9f8fc}
.home-footer-inner{grid-template-columns:1.35fr .9fr;gap:34px;align-items:start}
.footer-logo-area{grid-row:span 2}
.footer-logo-grid{display:grid;gap:12px}
.logo-tile{border-radius:6px;padding:14px;display:flex;align-items:center;justify-content:center;min-height:82px;overflow:hidden}
.logo-tile-light{background:#fff;border:1px solid rgba(255,255,255,.55)}
.logo-tile-dark{background:#03485d;border:1px solid rgba(255,255,255,.22)}
.logo-tile img{max-width:100%;max-height:92px;width:auto;height:auto;display:block}
.logo-tile-small img{max-height:118px}
.footer-contact-area h3,.footer-acknowledgment h3{color:#fff;text-transform:uppercase;letter-spacing:.06em;font-size:13px;margin:0 0 12px}
.footer-contact-area p,.footer-acknowledgment p{margin:0 0 14px;color:#e9f8fc;line-height:1.6}
.footer-contact-area a{color:#fff;font-weight:750}
.license-text{font-size:12px;color:#d4edf5;border-top:1px solid rgba(255,255,255,.18);padding-top:14px;margin-top:16px!important}
.copyright-text{font-size:12px;color:#d4edf5}
.footer-acknowledgment{grid-column:2;border-top:1px solid rgba(255,255,255,.18);padding-top:18px}
@media(max-width:900px){.home-io-grid{grid-template-columns:1fr}.home-footer-inner{grid-template-columns:1fr}.footer-logo-area,.footer-acknowledgment{grid-column:auto;grid-row:auto}.research-item p{padding:18px 22px}.research-heading{align-items:flex-start}.home-hero p{font-size:18px}}


/* Unified institutional footer */
.site-footer{
  background:#087b98;
  color:#fff;
  margin-top:48px;
}
.site-footer-inner{
  max-width:1230px;
  margin:0 auto;
  padding:54px 34px 42px;
}
.footer-logo-row{
  display:grid;
  grid-template-columns:repeat(3, minmax(0, 1fr));
  align-items:center;
  justify-items:center;
  column-gap:36px;
  margin-bottom:36px;
}
.footer-logo{
  display:block;
  width:100%;
  height:auto;
  object-fit:contain;
}
.footer-logo-mgri{max-width:245px;justify-self:center;}
.footer-logo-hms{max-width:245px;justify-self:center;}
.footer-logo-baylor{max-width:110px;justify-self:center;}
.footer-content-row{
  display:grid;
  grid-template-columns:minmax(320px,1fr) minmax(320px,.9fr);
  gap:110px;
  align-items:start;
}
.site-footer h2{
  color:#fff;
  text-transform:uppercase;
  font-size:18px;
  line-height:1.3;
  font-weight:500;
  letter-spacing:.01em;
  margin:0 0 20px;
}
.site-footer p{
  color:#fff;
  font-size:18px;
  line-height:1.6;
  margin:0;
}
.site-footer a{
  color:#fff;
  text-underline-offset:3px;
}
.footer-contact-block strong{font-weight:500;}
.footer-ack-block p{max-width:430px;}
.footer-small-rule{
  width:100px;
  border-top:2px solid rgba(255,255,255,.45);
  margin:26px auto 28px;
}
.footer-link-row{
  display:flex;
  justify-content:center;
  gap:30px;
  font-size:18px;
  font-weight:800;
}
.footer-link-row a{text-decoration:none;}
.footer-link-row a:hover{text-decoration:underline;}
.footer-license{
  max-width:820px;
  margin:44px auto 0!important;
  text-align:center;
  font-size:17px!important;
  line-height:1.55!important;
}
.footer-copyright{
  margin-top:26px!important;
  text-align:center;
  font-size:17px!important;
}
@media(max-width:900px){
  .site-footer-inner{padding:40px 22px 34px;}
  .footer-logo-row{grid-template-columns:1fr;gap:24px;margin-bottom:36px;}
  .footer-logo-mgri,.footer-logo-hms,.footer-logo-baylor{justify-self:start;max-width:100%;}
  .footer-logo-mgri{max-width:260px;}
  .footer-logo-hms{max-width:260px;}
  .footer-logo-baylor{max-width:110px;}
  .footer-content-row{grid-template-columns:1fr;gap:34px;}
  .site-footer p{font-size:16px;}
  .site-footer h2{font-size:16px;}
  .footer-small-rule{margin-left:0;margin-right:0;}
  .footer-link-row{justify-content:flex-start;}
  .footer-license,.footer-copyright{text-align:left;font-size:15px!important;}
}


/* Site navigation logo */
.brand{display:inline-flex;align-items:center;gap:9px}
.brand .nav-logo{width:32px;height:32px;object-fit:contain;display:block;flex:0 0 auto}
@media(max-width:800px){.brand .nav-logo{width:30px;height:30px}}


/* Methods references */
.source-ref{font-weight:800;color:#075f78;}
.references-list{margin:14px 0 0;padding-left:24px;color:#1f2937;font-size:14px;line-height:1.55;}
.references-list li{margin:0 0 10px;padding-left:4px;}
.references-list li::marker{font-weight:800;color:#03485d;}

/* Keep compact numbered source references on one line in the Methods input table. */
.methods-table th:nth-child(3),
.methods-table td:nth-child(3),
.source-ref{
  white-space: nowrap;
}
.methods-table th:nth-child(3),
.methods-table td:nth-child(3){
  min-width: 132px;
}


/* Team photo cards */
.team-card-with-photo{
  display:grid;
  grid-template-columns:118px 1fr;
  gap:18px;
  align-items:center;
  min-height:154px;
}
.team-photo{
  width:118px;
  height:118px;
  object-fit:cover;
  border-radius:6px;
  border:1px solid var(--line);
  background:#f8fafc;
  display:block;
}
.team-card-copy h3{margin-top:0;}
@media(max-width:560px){
  .team-card-with-photo{grid-template-columns:92px 1fr;gap:14px;min-height:118px;}
  .team-photo{width:92px;height:92px;}
}